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The relationship between clinical effect and concentrations of temazepam in plasma and cerebrospinal fluid

✍ Scribed by A. C. MOFFAT; G. A. OSBORNE; N. R. BADCOCK; P. MARANUCCI; T. NYMAN; W. J. RUSSELL


Book ID
108625721
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
516 KB
Volume
50
Category
Article
ISSN
0003-2409

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Thirteen male patients were administered 20 mg of temazepam orally 1 to 2 h prior to undergoing spinal anaesthesia for a urological procedure. Samples of blood and CSF were drawn just before insertion of the spinal and the concentration of drug estimated in these two media. The results obtained indi