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The regulation of trefoil factor 2 expression by the transcription factor Sp3

✍ Scribed by Jingjing Liu; Xu Wang; Yiling Cai; Jingping Zhou; Bayasi Guleng; Huaxiu Shi; Jianlin Ren


Book ID
119194622
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
477 KB
Volume
427
Category
Article
ISSN
0006-291X

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## Abstract The transcription factors Sp1, Sp3, and Egr‐1 bind with their zinc finger DNA‐binding domains to GC‐rich sequences in the regulatory regions of their target genes. The similarity of the DNA‐binding sites of Sp1, Sp3, and Egr‐1 has triggered the hypothesis that they compete for the same