## Abstract Recent evidence indicates that transcription factor Runx1 modulates the expression of several phenotypic markers in dorsal root ganglia (DRGs) neurons, including the painβrelated P2X3 receptor. In several cell lineages C/EBP transcription factors interact with the Runx factor family mem
Regulation of NFATc2 gene expression by the transcription factor Runx2
β Scribed by Kannan Thirunavukkarasu; Yong Pei; Terry L. Moore; Tao Wei; He Wang; Srinivasan Chandrasekhar
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 366 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0301-4851
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The Runx (runt-related protein) family of transcription factors plays important roles in different tissues and cell lineages. Runx1 determines commitment to the hematopoietic cell lineage and Runx2 determines commitment to the osteoblastic lineage. Cbfbeta is required for Runx1- and Runx2-dependent
## Abstract Runx2 is a master transcription factor for chondrocyte and osteoblast differentiation and bone formation. However expression of Runx2 (by RTβPCR), has been reported in nonβskeletal tissues such as breast, T cells and testis. To better define Runx2 activity in nonβskeletal tissues, we ex
## Abstract The Cbfa1/Runx2 is an important transcription factor necessary for osteoblast differentiation and bone formation. However, the signaling pathways regulating Runx2 activity are just beginning to be understood. Inconsistencies between Runx2 mRNA or protein levels and its transcriptional a