The regioselective acylation of 2-methoxynaphthalene to 2-acetyl-6-methoxynaphthalene over zeolite beta

✍ Scribed by Sung Duk Kim; Kyung Hee Lee; Jae Sung Lee; Young Gul Kim; Kwang Eui Yoon

• Publisher: Elsevier Science
• Year: 2000
• Tongue: English
• Weight: 520 KB
• Volume: 152
• Category: Article
• ISSN: 1381-1169
• DOI: 10.1016/s1381-1169(99)00266-6

✦ Synopsis

The liquid phase acylation of 2-methoxynaphthalene 2-MON with acetic anhydride over various solid acid catalysts was investigated under controlled reaction conditions. Only zeolite beta exhibited good regioselectivities to desired 2-acetyl-6-Ž . methoxynaphthalene 2,6-AMON . Characterization studies of zeolite beta samples indicated that acidity affected catalytic activity but not regioselectivity of 2,6-AMON. The secondary structure of zeolite beta particles was found to be an important factor for the selectivity probably because of its effect on diffusion process of reactants into internal pores. When the mole of acetic anhydride used as acylating agent was increased, the selectivity of desired 2,6-AMON product became worse. 1,2-Dichloroethane and dichloromethane were found to be effective solvents giving good regioselectivities of 2,6-AMON.