The red blood cell Esterase D polymorphism in Europe and Asia
โ Scribed by R. A. Cartwright; I. L. Bethel; H. Hargreaves; M. Izatt; J. Jolly; R. J. Mitchell; K. S. Sawhney; M. Smith; E. Sunderland; D. Teasdale
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 330 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
โฆ Synopsis
Several regional series from Britain and 3 Asian series were typed for the Esterase D polymorphism. It was found that haemolysates up to 5 years old could be reliably typed when prepared from washed anticoagulated red blood cells. Lysates prepared from blood clots do not retain Esterase D activity quite as well. The Manx population has higher Esterase D 2 gene frequencies than neighbouring populations. A Nepalese population exhibits the highest Esterase D 2 gene frequency so far recorded. The other series presented supplement or confirm results already published.
๐ SIMILAR VOLUMES
630 individuals and 102 mother/child pairs from the Veneto provinces were examined for their red cell EsD by Cellogel electrophoresis. Compared with the horizontal starch-gel electrophoresis no differences in the zymogram patterns have been found. The gene frequencies observed (EsD 1 = 0.8556; EsD 2
Esterase-D phenotypes were determined in a population sample of Tuscany, Italy. The observed frequencies of the three alleles are: EsD1 = 0.856, EsD2 = 0.143 and EsD3 = 0.001. Studies of the pedigree of the propositus's EsD 3--1 family and mother-child combinations confirm an autosomal co-dominant i