Esterase-D phenotypes were determined in a population sample of Tuscany, Italy. The observed frequencies of the three alleles are: EsD1 = 0.856, EsD2 = 0.143 and EsD3 = 0.001. Studies of the pedigree of the propositus's EsD 3--1 family and mother-child combinations confirm an autosomal co-dominant i
Red cell esterase-D-polymorphism in the Veneto population
β Scribed by Cortivo, P. ;Breda, F. ;Ongaro, G. ;Bareggi, G. ;Ferraretto, L.
- Publisher
- Springer-Verlag
- Year
- 1978
- Tongue
- English
- Weight
- 122 KB
- Volume
- 81
- Category
- Article
- ISSN
- 1437-1596
No coin nor oath required. For personal study only.
β¦ Synopsis
630 individuals and 102 mother/child pairs from the Veneto provinces were examined for their red cell EsD by Cellogel electrophoresis. Compared with the horizontal starch-gel electrophoresis no differences in the zymogram patterns have been found. The gene frequencies observed (EsD 1 = 0.8556; EsD 2 = 0.1444) differ only slightly from those reported for various European populations and are nearly identical with data for other Italian populations. Family studies confirmed the Mendelian co-dominant inheritance.
π SIMILAR VOLUMES
Several regional series from Britain and 3 Asian series were typed for the Esterase D polymorphism. It was found that haemolysates up to 5 years old could be reliably typed when prepared from washed anticoagulated red blood cells. Lysates prepared from blood clots do not retain Esterase D activity q
The frequency of variant forms of 6 red cell enzymes, adenylate kinase, adenosine deaminase, phosphoglucomutase, acid phosphatase, 6-phosphogluconate dehydrogenase and glutathione reductase, were determined in 9 Greek populations. The frequencies of the variants in these populations were similar to