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The reactivity of chloramphenicol reduction products with DNA bases

✍ Scribed by Joanne H. Tocher; David I. Edwards; Andrea Thomas

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
508 KB
Volume
29
Category
Article
ISSN
0360-3016

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πŸ“œ SIMILAR VOLUMES

Chemical reactivity of protonated azirid
Chemical reactivity of protonated aziridine with nucleophilic centers of DNA bases
✍ O. Kikuchi; A. J. Hopfinger; G. Klopman πŸ“‚ Article πŸ“… 1980 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 718 KB

## Abstract A series of molecular orbital calculations, using MINDO/3 and CNDO/2L methods, have been used to characterize the chemical reaction of protonated aziridine with DNA nucleophilic base sites. The N‐7 atom of guanine is found to be the preferred alkylation site only when the O‐6 atom of gu