Chemical reactivity of protonated azirid
β
O. Kikuchi; A. J. Hopfinger; G. Klopman
π
Article
π
1980
π
Wiley (John Wiley & Sons)
π
English
β 718 KB
## Abstract A series of molecular orbital calculations, using MINDO/3 and CNDO/2L methods, have been used to characterize the chemical reaction of protonated aziridine with DNA nucleophilic base sites. The Nβ7 atom of guanine is found to be the preferred alkylation site only when the Oβ6 atom of gu