The reaction of N-tosyl-b-phenethylamines with a-chloro-a-phenylthioketones, leading to 1-benzoyl-and 1-pivaloyl-tetrahydroisoquinolines under modified Pictet-Spengler conditions, is described. The synthesis of O-methylvelucryptine employing this transformation as a key step is reported.
✦ LIBER ✦
The reaction of α-chloro-α-phenylthioketones with phenols: An alternative synthesis of benzofurans
✍ Scribed by Thomas V. Lee; Adam A. Galan; Christopher B. Chapleo
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 101 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4039
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