Reaction of α-chloro-α-phenylselenoesters with silyl enol ethers. Synthesis of α-phenylseleno-γ-keto esters and γ-butyrolactones

✍ Scribed by Claudio C. Silveira; Antonio L. Braga; Alessandra Machado; Gustavo L. Fiorin; Miguel J Dabdoub

• Publisher: Elsevier Science
• Year: 1996
• Tongue: French
• Weight: 263 KB
• Volume: 37
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(96)02151-x

✦ Synopsis

Sly1 enol ethers of ketones are alkylated with ethyl a-chloro-a-phenylseleno acetate la or with ethyl a-chloro-a-phenylseleno propionate lb, mediated by zinc bromide to give the corresponding a-phenylseleno-y-keto esters 3 in moderate to good yields.