## Abstract For Abstract see ChemInform Abstract in Full Text.
Synthesis of γ-butyrolactones via the ene reaction of ethyl α-chloro-α-phenylthioacetate and 1-alkenes
✍ Scribed by Kin-ya Akiba; Yasuhito Takasu; Makoto Wada
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 222 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Sly1 enol ethers of ketones are alkylated with ethyl a-chloro-a-phenylseleno acetate la or with ethyl a-chloro-a-phenylseleno propionate lb, mediated by zinc bromide to give the corresponding a-phenylseleno-y-keto esters 3 in moderate to good yields.
## The 2-chloro-3-(2'~chloroalkyl)cyclopropenones 4, readily obtained by hydrolysis of the adducts of the m'chlorocyclopropenylium ion onto alkenes, thermally rearrange to propiolic acid chlorides 6. Treatment of 4 with TosOHJ+O in CH,Cl, yields the (E)-3-chloro-2-(2'-chloroalkyl)acrylic acids 9, wh
An efficient synthesis of indenoindene-fused a-methylene-c-butyrolactones was carried out via a tandem intra-and intermolecular Friedel-Crafts reaction from the spiro-lactone, which can be easily prepared from ninhydrin by indium-mediated Barbier reaction of cinnamyl bromide.