The reaction of thioesters with nitriles
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Antonio Herrera; Roberto MartΔ±Μnez-Alvarez; Pedro Ramiro
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Article
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2003
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Elsevier Science
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French
β 138 KB
Alkyl and S-aryl thioesters react with nitriles in the presence of triflic anhydride to form substituted 4-alkylthio-and 4-arylthiopyrimidines. However, when methyl thiocyanate is used as nitrile, dithioimidocarbonates are formed. A mechanism to explain these differences is postulated.