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The reaction of melicopine with bromine

✍ Scribed by R.H. Prager; H.M. Thredgold


Publisher
Elsevier Science
Year
1966
Tongue
French
Weight
229 KB
Volume
7
Category
Article
ISSN
0040-4039

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✦ Synopsis


In connection with some other work, a method was required for obtaining 7-bromomelicopine, I, from melicopine (1).

The first method attempted was the bromination of q elicopine, II, in acetic acid. By analogy with the work of Acheson ( 2) on E-β€’ethylacridone, which rezsdily formed ?,74ibromo-E-methylacridone in acetic acid, bromination was expected to proceed smoothly. The products isolated from this reaction mixture, however, were 7-bromonormelicopine (III: l&b), normelicopine (IV: 6,~) and the quinones V (10);) and VI (5'~).


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