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The reaction of Digitoxin and Digoxin with cyanoacetic acid hydrazide: Synthesis of Coumarin, Thiazole, Thiophene and Pyridine derivatives with potential biological activities

✍ Scribed by Senot H. Doss; Wagnat W. Wardakhan; Nadia A. Louca


Publisher
Springer
Year
2001
Tongue
English
Weight
658 KB
Volume
24
Category
Article
ISSN
0253-6269

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The reaction of 2-amino-3-cyano-4,5,6,7-
✍ Rafat M. Mohareb; Fatma A. El-Omran; Jonathan Z. Ho 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB

## Abstract The reaction of 2‐amino‐3‐cyano‐4,5,6,7‐tetrahydrobenzo[b]thiophene (**1**) with diethyl malonate (**2**) gave two products: **3** and **4**. The reactivity of **3** toward a variety of chemical reagents was studied to give azoles, azines, and their fused derivatives. © 2001 John Wiley