The reaction of amines with phthalimide derivatives a convenient synthesis of isoxazolidine
β Scribed by M. Bouzoubaa; G. Leclerc
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 194 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
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## Abstract For Abstract see ChemInform Abstract in Full Text.
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Boc-(R)-ot-phenylproline ethyl ester 1 was prepared in good yield starting from racemic phenylglycine. Condensation of phenylglycine ethyl ester with benzaldehyde furnished N-benzylidene phenylglycine ethyl ester which was allylated under phase transfer catalysis conditions. After acidic hydrolysis,
## Abstract The reaction of enolates of Ξ±βunsubstituted carboxamides 3 with diphenyl phosphorazidate (DPPA) and di(__tert__βbutyl) dicarbonate (βBoc anhydrideβ) in THF at β78Β° yielded 2β{[(__tert__βbutoxy)carbonyl]amino}carboxamides 5 (__Scheme 2__) which are derivatives of Ξ±βamino acids. In this r