## Abstract Age‐specific incidence curves of mouse breast cancer suggest a rate‐limiting step in tumor progression one step prior to overt cancer and the withdrawal prior to middle life of a critical etiological condition (hormonal?) for one or more of the earlier steps in the oncogenic sequence.
✦ LIBER ✦
The rate-limiting steps of the rising phase of miniature end plate currents in the mouse diaphragm
✍ Scribed by F. Tanzi; H. D'Angelo; M. Toselli; V. Taglietti
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 371 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1567-5394
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Rate-limiting step in the progression of
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Thyroid hormones regulate the frequency
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Thyroid hormones (THs), primarily 3,3',5-triiode-(L)-thyronine (T(3)), have been clearly established as natural inducers of apoptosis during metamorphosis of anuran embryos. We decided to use this phenomenon to test the hypothesis that, prior to genomic activation, T(3) has acute actions in the neur