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The radical scavenger edaravone counteracts diabetes in multiple low-dose streptozotocin-treated mice

โœ Scribed by Daisuke Fukudome; Maki Matsuda; Toshiyuki Kawasaki; Yukio Ago; Toshio Matsuda


Book ID
113587426
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
266 KB
Volume
583
Category
Article
ISSN
0014-2999

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To investigate early immunological disturbances at the onset of diabetes, lymphocyte function and islet cell surface antibodies were studied in streptozotocin-treated C57BL/10 and B10.BR mice. In C57BL/10 mice, streptozotocin given in multiple low doses depressed lymphoblastic transformation to phyt