Convenient syntheses of N-CD3 labelled n
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Jeffrey I. Seeman; Henry V. Secor; Gary Forrest
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Article
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1979
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John Wiley and Sons
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French
β 321 KB
Two procedures for the preparation of N-CD3 labelled nicotine and nicotine analogues are reported. These include: (a) the deuteroiodomethylation of the lithium amide of the corresponding secondary m i n e ; and (b) the alkylation of the corresponding cyclic imine followed by sodium cyanoborohydride