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The rabbit biodistribution of a therapeutic dose of zoledronic acid labeled with Tc-99m

✍ Scribed by Makbule Asikoglu; Funda Gamze Durak


Book ID
103817323
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
250 KB
Volume
67
Category
Article
ISSN
0969-8043

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A series of salicylidene-aminoacid Schiff bases was synthesized and labeled with Tc-99m, in neutral pH, using stannous ion as reductant. Labeling yield was greatly affected by concentration-ratios of the reactants, the optimum concentration ratio being 18.5 x 1 O-2nuno1 ligand to 0.4 x 10-2mmol SnC1