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The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling

✍ Scribed by Francisca Vazquez; William R Sellers

Book ID
114223016
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
415 KB
Volume
1470
Category
Article
ISSN
0304-419X

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## Glioblastomas are highly malignant tumors of the central nervous system that are resistant to radiation and chemotherapy [1]. We explored the role of the phosphatidylinositol (PI) 3-kinase signal transduction pathway in glioblastomas, as this pathway has been shown to inhibit apoptosis induced b