The protein kinase inhibitor, H-7, suppresses heat-induced activation of heat shock transcription factor 1
β Scribed by Ken Ohnishi; Xinjiang Wang; Akihisa Takahashi; Hideki Matsumoto; Takeo Ohnishi
- Book ID
- 110244196
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 87 KB
- Volume
- 197
- Category
- Article
- ISSN
- 0300-8177
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The activation of heat shock transcription factor-1 (HSF-1) after treatment of mammalian cells with stresses such as heat shock, heavy metals, or ethanol induces the synthesis of heat shock proteins. HSF-1 is phosphorylated at normal growth temperature and is hyperphosphorylated upon stress. We rece
## Abstract BAG3 protein, a member of the BAG coβchaperones family, sustains cell survival in a variety of normal and neoplastic cell types, via its interaction with a variety of partners, such as the heat shock protein (HSP) 70, Bclβ2, Rafβ1 and others. Expression of BAG3 is induced by some stress