𝔖 Bobbio Scriptorium
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THE PROTEIN BINDING AND ELIMINATION OF METHOTREXATE AFTER INTRAVENOUS INFUSIONS IN CANCER PATIENTS

✍ Scribed by James W. Paxton


Book ID
108933068
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
502 KB
Volume
9
Category
Article
ISSN
0305-1870

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Pharmacokinetic modeling of plasma and c
✍ E. Chatelut; H. Roche; Y. Plusquellec; F. Peyrille; J. De Biasi; A. Pujol; P. Ca πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 436 KB

A pharmacokinetic study was performed in plasma and cerebrospinal fluid (CSF) of patients suffering from brain tumors to describe the disposition of methotrexate. An open three-compartment model was developed to fit together the data obtained in plasma and CSF. The pharmacokinetic parameters obtaine