The protective effects of physiological and pharmacological concentrations of melatonin on renal ischemia-reperfusion injury in rats
β Scribed by Sahna, Engin ;Parlakpinar, Hakan ;Ozturk, Feral ;Cigremis, Yilmaz ;Acet, Ahmet
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 530 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0300-5623
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## Abstract Renal ischemiaβreperfusion injury occurs in many clinical conditions such as hypovolemic shock, thromboembolism, injury and after renal transplantation. Under these conditions, ROS are considered to be the reason for cellular damage. Bioflavonoids have antioxidant and renoprotective pro
To investigate the protective effects of ligustrazine on renal ischemia-reperfusion injury, the influence of ligustrazine injection on plasma superoxide dismutase (SOD), malondialdehyde (MDA), and endothelin-1 (ET-1), as well as changes of morphology of renal tubules, were studied in rat kidney mode