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The prognostic role of histological grade and c-erbB-2 oncogene amplification in primary tumors of metastatic breast cancer

✍ Scribed by Niskanen, E.; Franssila, K.; Blomqvist, C.; Hietanen, P.; Wasenius, V-M.

Book ID
122599890
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
160 KB
Volume
29
Category
Article
ISSN
0959-8049

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Alterations in the gene copy numbers of the proto-oncogenes HERZ/neu and c-myc in primary human breast cancer investigated in 73 patients. We detected amplification of H€R2/ neu in 17 patient samples and amplification of c-myc in I I, while amplification of both was seen in 6 samples. There was no c