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The profile of repeat-associated histone lysine methylation states in the mouse epigenome

✍ Scribed by Martens, Joost H A; O'Sullivan, Roderick J; Braunschweig, Ulrich; Opravil, Susanne; Radolf, Martin; Steinlein, Peter; Jenuwein, Thomas

Book ID
110030941
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
858 KB
Volume
24
Category
Article
ISSN
0261-4189

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## Background In the mouse zygote the paternal genome undergoes dramatic structural and epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and DNA is rapidly and actively demethylated. The epigenetic asymmetry between parental genomes remains at least until the 2-cell