The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m -AMSA

The production of topoisomerase II-media

The production of topoisomerase II-mediated DNA cleavage in human leukemia cells predicts their susceptibility to 4′-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA)

✍ Milorad Bakic; Miloslav Beran; Borje S. Andersson; Lynn Silberman; Elihu Estey; 📂 Article 📅 1986 🏛 Elsevier Science 🌐 English ⚖ 375 KB

The interaction between nuclear topoisom

The interaction between nuclear topoisomerase II activity from human leukemia cells, exogenous DNA, and 4′-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA) or 4-(4,6-0-ethylidene-β-D-glucopyranoside) (VP-16) indicates the sensitivity of the cells to the drugs

✍ Elihu H. Estey; Lynn Silberman; Miloslav Beran; Borje S. Andersson; Leonard A. Z 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 590 KB

Sister-chromatid exchanges, chromosomal

Sister-chromatid exchanges, chromosomal aberrations and cytotoxicity produced by topoisomerase II-targeted drugs in sensitive (A2780) and resistant (A2780-DX3) human ovarian cancer cells: Correlations with the formation of DNA double-strand breaks

✍ Elvira Noviello; MariaGrazia Aluigi; Guido Cimoli; Elisabetta Rovini; Alessandra 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 625 KB

Bio-Assays for Oxidative Stress Status |

Bio-Assays for Oxidative Stress Status || IN VIVO TOTAL ANTIOXIDANT CAPACITY: COMPARISON OF DIFFERENT ANALYTICAL METHODS11Mention of a trade name, proprietary product, or specific equipment does not constitute a guarantee by the U.S. Department of Agriculture and does not imply its approval to the exclusion of other products that may be suitable.Address correspondence to: R. L. Prior, Ph.D., USDA, ARS, HNRCA, 711 Washington St., Boston, MA 02111, USA; Tel: (617) 556–3311; Fax: (617) 556-3222; E-Mail: [email protected]. Ronald Prior is a Nutritionist and Laboratory Chief of the Phytochemical Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University, Boston, MA. Dr. Prior received his B.S. degree with honors from the University of Nebraska and he received his Ph.D. in Nutrition and Biochemistry from Cornell University in 1972. Dr. Prior has worked with the USDA for more than 20 years.During the past 12 years at the HNRCA, he has been Scientific Program Officer and has directed research activities dealing with the role of flavonoid and other phenolic food components on antioxidant status, their metabolism, and relationships to diseases of aging.Guohua Cao, M.D., Ph.D., is currently a Scientist II at HNRCA. Dr. Cao studied medicine in Nantong Medical College in 1979 and at Nanjing Medical University in 1984. He obtained his Ph.D. in nutritional biochemistry from Beijing Medical University in 1990. Dr. Cao came to the United States in 1991 and worked at NIH where he was instrumental in developing the ORAC method.

✍ PRIOR, RONALD L. 📂 Article 📅 2001 🏛 Elsevier 🌐 English ⚖ 986 KB

This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, *Free Radical Biology & Medicine*. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal