𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The processing of native and mutant APP751 in human 293 cells


Book ID
122619382
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
346 KB
Volume
13
Category
Article
ISSN
0197-4580

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## Abstract The amyloid precursor protein (APP) is cleaved enzymatically by nonamyloidogenic and amyloidogenic pathways. α‐Secretase (α‐secretase), cleaves APP within the β‐amyloid (Aβ) sequence, resulting in the release of a secreted fragment of APP (αAPPs) and precluding Aβ generation. In this st