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The prevention of diabetes using rosiglitazone in the non-obese diabetic mouse

✍ Scribed by Beales, Philip E; Rosignoli, Guglielmo; Batchelor, Kenneth; Pozzilli, Paolo

Book ID: 123418925
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 144 KB
Volume: 50
Category: Article
ISSN: 0168-8227
DOI: 10.1016/S0168-8227(00)81324-8

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Background The non-obese diabetic (NOD) mouse is a widely used model of Type 1 diabetes mellitus (Type 1 DM), which displays many of the characteristics of the disease found in humans. Nicotinamide (NA) is currently being tested in large-scale, multi-centre human trials for the prevention of Type 1