## Abstract We report the neuropathological findings in a patient with Parkinson's disease (PD) associated with Basque R1441G‐__LRRK2__/dardarin mutation. The patient was a man with disease onset at 68 years of age, with unilateral rest tremor; the Parkinsonism was well controlled with medication f
The prevalence of the G2019S and R1441C/G/H mutations in LRRK2 in German patients with Parkinson’s disease
✍ Scribed by J. C. Möller; I. Rissling; V. Mylius; C. Höft; K. M. Eggert; W. H Oertel
- Book ID
- 111065507
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 61 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1351-5101
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract It has been proposed that olfactory tests and metaiodobenzylguanidine cardiac scintigraphy may help diagnose idiopathic Parkinson's disease in the premotor phase. However, it is not clear what value these tests have in all patients with Parkinson's disease and, particularly, in those wh
To evaluate the frequency of the LRRK2 G2019S mutation in Italy, we tested 1,072 probands with Parkinson's disease (PD; 822 sporadic and 250 familial): 20 patients (1.9%) carried the G2019S mutation, 11 patients (1.3%) were sporadic, and 9 (4.3%) had a positive family history. Considering only proba