## Abstract We report the neuropathological findings in a patient with Parkinson's disease (PD) associated with Basque R1441Gโ__LRRK2__/dardarin mutation. The patient was a man with disease onset at 68 years of age, with unilateral rest tremor; the Parkinsonism was well controlled with medication f
Cognitive dysfunction in Parkinson's disease related to the R1441G mutation in LRRK2
โ Scribed by Estanga, A.; Rodriguez-Oroz, M.C.; Ruiz-Martinez, J.; Barandiaran, M.; Gorostidi, A.; Bergareche, A.; Mondragon, E.; Lopez de Munain, A.; Marti-Masso, J.F.
- Book ID
- 127328250
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 324 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1353-8020
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## Abstract The __LRRK2 R1441G__ mutation was first identified in Basque families and it is responsible for 46% of familial Parkinson's disease (PD) and for 2.5% of sporadic PD in the PD population of Basque ascent. The aim of this study was to determine __LRRK2 R1441G__ penetrance in PD in the Bas
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