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The prevalence of the 235delC GJB2 mutation in a Chinese deaf population

✍ Scribed by Dai, Pu; Yu, Fei; Han, Bing; Yuan, Yongyi; Li, Qi; Wang, Guojian; Liu, Xin; He, Jia; Huang, Deliang; Kang, Dongyang; Zhang, Xin; Yuan, Huijun; Schmitt, Eric; Han, Dongyi; Wong, Lee-Jun


Book ID
125845166
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
456 KB
Volume
9
Category
Article
ISSN
1098-3600

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We have investigated the prevalence of mutations in the connexin 26 (GJB2) gene in Omani population using both PCR-RFLP and direct DNA sequencing methods. Two common GJB2 gene mutations (35delG and 167delT) were screened in 280 healthy controls and 95 deaf patients using two different PCR-RFLP metho