Spectrum of GJB2 mutations causing deafness in the British Bangladeshi population
โ Scribed by Y. Bajaj; T. Sirimanna; D.M. Albert; P. Qadir; L. Jenkins; M. Bitner-Glindzicz
- Book ID
- 111391271
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 109 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1749-4478
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Genetic testing was completed on 1,294 persons with deafness referred to the Molecular Otolaryngology Research Laboratories to establish a diagnosis of DFNB1. Exon 2 of GJB2 was screened for coding sequence allele variants by denaturing high-performance liquid chromatography (DHPLC) complemented by
We have investigated the prevalence of mutations in the connexin 26 (GJB2) gene in Omani population using both PCR-RFLP and direct DNA sequencing methods. Two common GJB2 gene mutations (35delG and 167delT) were screened in 280 healthy controls and 95 deaf patients using two different PCR-RFLP metho