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The presence of candidate tumor suppressor gene loci at chromosome 3p for oral squamous cell carcinomas

✍ Scribed by Kazuo Arai; Takahiko Shibahara; Nobuharu Yamamoto; Hiroyasu Noma

Book ID: 114393929
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 650 KB
Volume: 38
Category: Article
ISSN: 1368-8375
DOI: 10.1016/s1368-8375(02)00068-4

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## Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity, representing ˜90% of all oral carcinomas and accounting for 3–5% of all malignancies. The __WWOX__ gene (WW‐domain containing oxidoreductase) is a candidate tumor suppressor gene located at 16q