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The preparation of 5-substituted and 3,5-disubstituted isothiazoles by nucleophilic displacement reactions of the corresponding methylsulphonyl compounds

✍ Scribed by Davis, Michael; Gordon, J. A.


Book ID
111892217
Publisher
Royal Society of Chemistry
Year
1972
Weight
224 KB
Volume
0
Category
Article
ISSN
1472-7781

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Purine n-oxides XXIV. The preparation of
✍ Uwe WΓΆlcke; Nigel J.M. Birdsall; George Bosworth Brown πŸ“‚ Article πŸ“… 1969 πŸ› Elsevier Science 🌐 French βš– 188 KB

In a recent publication (2) on the rearrangement of purine j-N-oxides to 8-hydroxypurines in acid anhydrides, a postulated intermediate was the 0-acyl derivative of the N-oxide. Such an intermediate, 3-acetoxyxanthine (II), [ctx5 267 mp (E 14,000)], has now been prepared by