The preparation of 2,4-dibromoestra- 1,3,5(10),6-tetraene-3,17 β-diol diacetate
✍ Scribed by Zsuzsanna Szendi; György Dombi; Iren Vincze
- Book ID
- 116065599
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 347 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0039-128X
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Contrary to a report (1) in the literature that estrone-16 (16-keto-estra-1,3,5(10)-trien-3-01) (2) fails to form an enol acetate, we have found that, with the aid of anhydrous E-toluenesulfonic acid as a catalyst, estra-1,3,5(1C),16-tetraene-3, 16-diol diacetate can be successfully obtained in stab
The molecule of the title compound, C~20~H~34~O~4~, is centrosymmetric. In the crystal structure, a network of O—H...O hydrogen bonds result in each molecule being linked to four neighbouring molecules and a two-dimensional net is formed.