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The preparation, antischistosomal and antitumor activity of hycanthone and some of its congeners. Evidence for the mode of action of hycanthone

✍ Scribed by Archer, Sydney; Pica-Mattoccia, Livia; Cioli, Donato; Seyed-Mozaffari, Ahmad; Zayed, Abdel Hadi

Book ID
126126638
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
950 KB
Volume
31
Category
Article
ISSN
0022-2623

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✍ J. A. Wright; W. H. Lewis πŸ“‚ Article πŸ“… 1974 πŸ› John Wiley and Sons 🌐 English βš– 274 KB

## Abstract Hydroxyurea and guanazole were used as selective agents in tissue culture to obtain independent Chinese hamster ovary cell lines resistant to the cytotoxic effects of hydroxyurea or guanazole. In all cases tested a cell line selected for resistance to one of the antitumor agents exhibit