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The preparation and labeling of DTPA-coupled albumin

✍ Scribed by D.J. Hnatowich; W.W. Layne; R.L. Childs


Publisher
Elsevier Science
Year
1982
Weight
514 KB
Volume
33
Category
Article
ISSN
0020-708X

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Proton relaxation enhancement of albumin
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## Abstract Bovine serum albumin, immunoglobulin G, and fibrinogen were labeled with Gd‐DTPA using a bifunctional chelating agent DTPA anhydride. The protein‐(Gd‐DTPA) conjugates had 1.4‐ to 2.0‐fold greater longitudinal relaxivities at 0.02 and 0.44 T than the relaxivity of plain Gd‐DTPA. The incr