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The preparation and characterisation of111In-labelled 791T/36 monoclonal antibody for tumour immunoscintigraphy

✍ Scribed by Alan C. Perkins; Malcolm V. Pimm; Michael K. Birch

Publisher
Springer
Year
1985
Tongue
English
Weight
604 KB
Volume
10
Category
Article
ISSN
0340-6997

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Biodistribution and tumour localization
Biodistribution and tumour localization of a methotrexate-monoclonal-antibody 791T/36 conjugate in nude mice with human tumour xenografts
✍ M. V. Pimm; Jane A. Clegg; M. C. Garnett; R. W. Baldwin πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 717 KB

The blood kinetics and tumour localization of a conjugate of methotrexate (MTX) and MAb 791T136 were examined i n nude mice with human tumour xenografts. The antibod moiety of the conjugate was detected by labelling with l2J and the drug moiety was assayed using a radioimmunoassay for methotrexate.