✦ LIBER ✦

The Prediction of the Structural Class of Protein: Application of the Measure of Diversity

✍ Scribed by QIAN-ZHONG LI; ZHI-QING LU

Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 235 KB
Volume: 213
Category: Article
ISSN: 0022-5193
DOI: 10.1006/jtbi.2001.2441

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✦ Synopsis

Based on the concept that the structural class of a protein is mainly determined by its secondary structure sequence, a new algorithm for prediction of the structural class of a protein is proposed. By use of the number of -helices, -strands, and fragments, the structural class of a protein can be predicted by an algorithm based on the increment of diversity (ID), in which the sole prediction parameter*the increment of diversity is used as the index of prediction of structural class of a protein. The results indicate that the high rates of correct prediction are obtained for complete set (standard set) from Brookhaven Protein Data Bank-CD ROM (PDB) published in October 1995 and the test set newly released from Brookhaven Protein Data Bank-CD ROM (PDB) before July 1998, respectively.

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