We performed an analysis of inbreeding and kinship among the ascending genealogies of 205 autopsy-confirmed Alzheimer disease (AD) subjects recruited in the Saguenay area of QuΓ©bec. We hypothesized that if some traits pertaining to the disease were determined by inherited factors, and if the corresp
The power of systematic genealogical study in familial Alzheimer disease
β Scribed by A. C. Bruni; M. P. Montesi; I. Rainero; L. Ferini-Strambi; F. Macciardi; L. Pinessi; G. Gei; D. Fragiacomo; L. Bergamini
- Publisher
- Springer Milan
- Year
- 1993
- Tongue
- English
- Weight
- 368 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1590-1874
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Regional and global cerebral atrophy are inevitable features of Alzheimer's disease (AD). We assessed volumes and atrophy rates of brain structures in patients with familial AD during the period that they developed symptoms. Five patients with presymptomatic AD and 20 controls had two o
## Abstract Familial Alzheimer disease is a neurological disorder of adult onset. Three research centers have each contributed their families and genetic linkage data for combined analyses. The data from the Duke and Boston centers, comprising 73 pedigrees for whom numerous markers on chromosomes 1