The potentiation of arterial contraction with platelet activating factor
✍ Scribed by Mark Kester; Ronald F. Ledvora; Michael Bárány
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 490 KB
- Volume
- 400
- Category
- Article
- ISSN
- 0031-6768
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## Abstract Platelet‐activating factor (PAF) is a soluble signal messenger present in blood at nanomolar concentration. PAF has a wide spectrum of biological activities and is produced by and effective in different cell types. Owing to its important physiological role, we wanted to characterize mem
The synthesis of azathia analogues of the platelet activating factor with oxygen and sulphur-containing sidechains is reported. The starting point is 1-acetylthio-3-hydroxy-2-propaneamine-HCl, which permits the formation of the thioether and the acetamido linkage in one step. The phosphocholine part
## Abstract Embryo‐derived platelet activating factor (EPAF) is thought to be either biologically similar to platelet activating factor (PAF) or responsible for PAF liberation in vivo. We have previously shown that premating PAF treatment in the mouse renders the platelets nonresponsive to EPAF, le