๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

THE POTENTIAL OF FARNESYLTRANSFERASE INHIBITORS AS CANCER CHEMOTHERAPEUTICS 1

โœ Scribed by Gibbs, Jackson B.; Oliff, Allen


Book ID
115462094
Publisher
Annual Reviews
Year
1997
Tongue
English
Weight
176 KB
Volume
37
Category
Article
ISSN
0362-1642

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Development of inhibitors of protein far
โœ Nancy E. Kohl; Michael W. Conner; Jackson B. Gibbs; Samuel L. Graham; George D. ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 565 KB

Protein prenylation, adding either the 15-carbon isoprenoid farnesyl or the 20-carbon isoprenoid geranylgeranyl to cysteine residuek) at or near the C-termini of proteins, is a recently identified post-translational modification that localizes some proteins to a membrane compartment. One of the most