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The potential immunogenicity of human insulin and insulin analogues evaluated in a transgenic mouse model

✍ Scribed by J. L. Ottesen; P. Nilsson; J. Jami; D. Weilguny; M. Dührkop; D. Bucchini; S. Havelund; J. M. Fogh


Publisher
Springer
Year
1994
Tongue
English
Weight
1002 KB
Volume
37
Category
Article
ISSN
0012-186X

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## Abstract Multiple myeloma (MM) is a fatal disease that affects plasma cells. Patients with MM have 1 or more osteolytic lesions in their bone tissues, where insulin‐like growth factors (IGFs; IGF‐I and IGF‐II) are mainly stored. The role of bone‐derived IGFs in the development of MM has not been