To determine if hemizygous transgenic mice carrying the human c-Ha-ras gene (CB6F1-Tg Hras2 mice (Hras2 mice)) are susceptible to the carcinogenic potential of known murine carcinogens, male and female Hras2 mice and their non-transgenic CB6F1 littermates (non-Tg mice) were each given a single intra
Hyperinsulinemia in transgenic mice carrying multiple copies of the human insulin gene
β Scribed by Marban, S. L. ;Deloia, J. A. ;Gearhart, J. D.
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 878 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0192-253X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Communicated by Richard G.H. Cotton Interindividual differences in human CYP1A1 and CYP1A2 expression appear to be associated with variability in risk toward various types of environmental toxicity and cancer. These two genes are oriented head-to-head on human chromosome 15; the 23.3-kb spacer
Mutations in the b-subunit of cGMP-phosphodiesterase (PDE6b) can lead to either progressive retinal disease, such as human retinitis pigmentosa (RP), or stationary disease, such as congenital stationary night blindness (CSNB). Individuals with CSNB in the Rambusch pedigree were found to carry the H2
The flavonoid chrysin is an important dietary substance and induces UGT1A1 protein expression in cell culture. As a representative of the class of dietary flavonoids, clinical investigations have been considered as a means of inducing hepatic UGT1A1 expression. We demonstrate the necessity of a xeno
## Abstract ## Background An Erratum has been published for this article in Journal of Gene Medicine 7(6), 2005, 836. Gene therapy is being studied as the next generation therapy for hemophilia and several clinical trials have been carried out, albeit with limited success. To explore the possibi