𝔖 Bobbio Scriptorium
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The possible significance of intracellular pH in insulin release

✍ Scribed by Willy J. Malaisse; André Herchuelz; Abdullah Sener


Book ID
118939449
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
208 KB
Volume
26
Category
Article
ISSN
0024-3205

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✍ Willy J. Malaisse; Pierre O. Plasman; François Blachier; Andre Herchuelz; Abdull 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 559 KB

The possible relevance of changes in extracellular and/or intracellular pH to the insulinotropic action of L-arginine and L-homoarginine was investigated in rat pancreatic islets. A rise in extracellular pH from 7.0 to 7.4 and 7.8 augmented the secretory response to these cationic amino acids whilst