Stimulus-secretion coupling of arginine-
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Willy J. Malaisse; Pierre O. Plasman; François Blachier; Andre Herchuelz; Abdull
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Article
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1991
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John Wiley and Sons
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English
⚖ 559 KB
The possible relevance of changes in extracellular and/or intracellular pH to the insulinotropic action of L-arginine and L-homoarginine was investigated in rat pancreatic islets. A rise in extracellular pH from 7.0 to 7.4 and 7.8 augmented the secretory response to these cationic amino acids whilst