We examined D 2 -dopamine receptor containing neurons in cultures of neonatal rat striatum for apoptosis following dopamine treatment. Exposure to cultures to micromolar concentrations of dopamine resulted in 60-70% killing of D 2 -dopamine receptor neurons within 24 hr. We also utilized a double la
β¦ LIBER β¦
The possible role of 2-hydroxyestradiol in the development of estrogen-induced striatal dopamine receptor hypersensitivity
β Scribed by J. Kirk Clopton; John H. Gordon
- Book ID
- 118870152
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 877 KB
- Volume
- 333
- Category
- Article
- ISSN
- 0006-8993
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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a KrebsβHEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am