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The possible absence of cytochrome P-450 linked xenobiotic metabolism in helminths

โœ Scribed by Precious, Wendy Y.; Barrett, John


Book ID
121957056
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
357 KB
Volume
992
Category
Article
ISSN
0304-4165

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Interaction of benzanthrone with cytochr
โœ Das, Mukul ;Garg, Kalpana ;Joshi, Anjulika ;Singh, Giriraj B. ;Khanna, Subhash K ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 783 KB

23%-34%), although the other enzyme, quinone reductase, which helps in the removal of toxic quinones, was found to be elevated (184%-199%). These results suggest several mechanisms by which benzanthrone may inhibit P450. This impairment of xenobiotic metabolism as well as the enhancement of lipid pe