## Abstract Pure neural leprosy (PNL) is often difficult to diagnose when acidβfast bacilli (AFB) cannot be detected. We undertook the present study to evaluate use of the polymerase chain reaction (PCR) in diagnosing PNL. Fiftyβeight patients (41 men and 17 women) suspected of pure neural leprosy
The polymerase chain reaction and cancer diagnostics
β Scribed by John Lyons
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 570 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
In this review, I describe the polymerase chain reaction (PCR) and its application to cancer diagnostics. I present recent improvements to PCR methodology, and describe some state-of-the-art detection methods and approaches used to diagnose various cancer markers, including ras genes, BCR/abl translocations, and G-proteins. Cancer
π SIMILAR VOLUMES
A mathematical model for polymerase chain reaction (PCR) is developed, taking into account the three steps in this process: melting of DNA; primer annealing; and DNA synthesis (polymerization). Activity and deactivation of the polymerase enzyme as a function of temperature is incorporated in the kin