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The polyhydroxylated fullerene derivative C60(OH)24 protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction

✍ Scribed by Xiaoqing Cai; Jiejie Hao; Xiaoyong Zhang; Bozhang Yu; Jinming Ren; Cheng Luo; Qingnuan Li; Qing Huang; Xianglin Shi; Wenxin Li; Jiankang Liu

Book ID
113924658
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
1013 KB
Volume
243
Category
Article
ISSN
0041-008X

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Polyhydroxylated fullerene derivative C60(OH)24 prevents mitochondrial dysfunction and oxidative damage in an MPP+-induced cellular model of Parkinson's disease
✍ Xiaoqing Cai; Haiqun Jia; Zhongbo Liu; Bei Hou; Cheng Luo; Zhihui Feng; Wenxin L 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 799 KB

## Abstract To find effective agents for Parkinson's disease (PD) prevention and therapy, we examined the protective effects of the polyhydroxylated fullerene derivative C~60~(OH)~24~ in a 1‐methyl‐4‐phenylpyridinium (MPP^+^)‐induced acute cellular PD model in human neuroblastoma cells and the free