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The poly(A)-binding protein facilitates in vitro translation of poly(A)-rich mRNA

✍ Scribed by Maria-Fatima GROSSI de SA; Nancy STANDART; Cezar MARTINS de SA; Omar AKHAYAT; Michèle HUESCA; Klaus SCHERRER

Book ID
115125957
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
687 KB
Volume
176
Category
Article
ISSN
1432-1327

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✍ Alan Sachs; Ronald Davis 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 50 KB

Depletion of the essential poly(A)-binding protein (PAB) in Saccharomyces cerevisiae by promoter inactivation or by the utilization of a temperature-sensitive mutation (pab1-F364L) results in the inhibition of translation initiation and poly(A) tail shortening1. Reversion analysis of pab1-F364L yiel